Cayman Saracatinib; Purity- Greater Than Or Equal To 90%; Size- 1

GSK180736A is an inhibitor of Rho-associated kinase 1 (ROCK1; IC₅₀ = 14 nM) and G protein-coupled receptor kinase 2 (GRK2; IC₅₀ = 0.77 µM).^, It is selective for GRK2 over GRK1, GRK5, and PKA (IC₅₀ = >100 µM for all) and selective for ROCK1 over RSK1 and p20S6K (IC₅₀s = 3,100 and 2,850 nM, respectively).^, GSK180736A increases maximum contractility in isolated mouse cardiomyocytes when used at a concentration of 1 µM.

WARNING This product is not for human or veterinary use.