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Cayman Azd 8330; Purity- Greater Than Or Equal To 98%; Size- 50 M
Cayman Azd 8330; Purity- Greater Than Or Equal To 98%; Size- 50 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$1,041.00
Your Price
$1,041.00
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | CAYM-11588-50 |
MFG.PART: | 11588-50 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
AZD 8330 is a selective allosteric inhibitor of MEK1/2 (IC50 = 7 nM). It blocks phosphorylation of ERK1/2 and inhibits proliferation of certain cancer cells.1 AZD 8330 is orally bioavailable, inhibits ERK phosphorylation in vivo, and reduces tumor growth in a Calu-6 nude rat xenograft model.2
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2-[(2-fluoro- 4-iodophenyl) amino]-1,6-di hydro-N-(2- hydroxyethoxy)- 1,5-dimethyl- 6-oxo-3-pyridine carboxamide
CAS Number
869357-68-6
Synonyms
- ARRY-424704
Molecular Formula
C16H17FIN3O4
Formula Weight
461.2
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 30 mg/ml
- DMSO: 30 mg/ml
- DMSO:PBS(pH 7.2) (1:2): 0.33 mg/ml
- Ethanol: 10 mg/ml
λmax
245, 321 nm
SMILES
FC1=C(NC(N2C)=C(C(NOCCO)=O)C=C(C)C2=O)C=CC(I)=C1
InChi Code
InChI=1S/C16H17FIN3O4/c1-9-7-11(15(23)20-25-6-5-22)14(21(2)16(9)24)19-13-4-3-10(18)8-12(13)17/h3-4,7-8,19,22H,5-6H2,1-2H3,(H,20,23)
InChi Key
RWEVIPRMPFNTLO-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 4 years
SKU | CAYM-11588-50 |
---|---|
Supplier Part Number | 11588-50 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/11588m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 50 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | Y |
CAS Number | 869357-68-6 |