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Cayman Alphaboswellic Acid; Purity- Greater Than Or Equal To 98
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NETA PART: | CAYM-11692-10 |
MFG.PART: | 11692-10 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Nicotinamide riboside is a riboside form of nicotinamide (Item No. ) that is found in trace amounts in yeast-containing and milk-derived products. It is a precursor of NAD+ (Item No. ) and a source of vitamin B3 (niacin). Nicotinamide riboside increases intracellular and mitochondrial NAD+ content in C2C12, Hepa1.6, and HEK293 cells in a concentration-dependent manner at concentrations ranging from 1-1,000 μM. It also decreases acetylation of FOXO1 and SOD2, which are substrates of sirtuin 1 (SIRT1) and SIRT3, respectively, but not the SIRT2 substrate tubulin, indicating nicotinamide riboside selectively enhances SIRT1 and 3 deacetylase activity. Nicotinamide riboside (400 mg/kg per day) increases NAD+ levels in liver and skeletal muscle and prevents body weight gain in mice fed a high-fat diet. It also increases NAD+ in the cerebral cortex and reduces cognitive deterioration in a transgenic mouse model of Alzheimer’s disease.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name | 3-(aminocarbonyl)-1-β-D-ribofuranosyl-pyridinium |
CAS Number | 1341-23-7 |
Molecular Formula | C11H15N2O5 |
Formula Weight | 255.3 |
Purity | ≥95% Contains ~80% cyclodextrin as stabilizer |
Formulation | A low-melting semi-solid |
Solubility |
|
SMILES | NC(C1=C[N+]([C@H]2[C@H](O)[C@H](O)[C@@H](CO)O2)=CC=C1)=O |
InChi Code | InChI=1S/C11H14N2O5/c12-10(17)6-2-1-3-13(4-6)11-9(16)8(15)7(5-14)18-11/h1-4,7-9,11,14-16H,5H2,(H-,12,17)/p+1/t7-,8-,9-,11-/m1/s1 |
InChi Key | JLEBZPBDRKPWTD-TURQNECASA-O |
Storage | -20°C |
Shipping | Room Temperature in continental US; may vary elsewhere |
Stability | ≥ 4 years |
SKU | CAYM-11692-10 |
---|---|
Supplier Part Number | 11692-10 |
UM | EA |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/11692m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | CN |
ProductLine | CAYM |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 471-66-9 |