Cayman Jervine; Purity- Greater Than Or Equal To 98%; Size- 10 Mg

Cayman Jervine; Purity- Greater Than Or Equal To 98%; Size- 10 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)

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NETA PART:	CAYM-11723-10
MFG.PART:	11723-10
UNSPSC:	12352200
Manufacturer:	Cayman

Description

Product Description

Jervine is a naturally occurring teratogenic alkaloid that inhibits the sonic hedgehog pathway (IC₅₀s = 500-700 nM) in vitro.¹ It induces a variety of birth defects in vivo, including holoprosencephaly, cyclopia, cebocephaly, exencephaly, and microphthalmia in rat, chicken, and sheep.^2,3,4 Jervine also reduces lipid accumulation and PPARγ and C/EBPα gene expression in 3T3-L1 adipocytes in vitro.⁵

WARNING This product is not for human or veterinary use.

Technical Information

Formal Name

(2’R,3S,3’R,3’aS,6’S,6aS,6bS,7’aR,11aS,11bR)-2,3,3’a,4,4’,5’,6,6’,6a,6b,7,7’,7’a,8,11a,11b-hexadecahydro-3-hydroxy-3’,6’,10,11b-tetramethyl-spiro[9H-benzo[a]fluorene-9,2’(3’H)-furo[3,2-b]pyridin]-11(1H)-one

CAS Number

469-59-0

Synonyms

NSC 7520
NSC 23898

Molecular Formula

C₂₇H₃₉NO₃

Formula Weight

425.6

Purity

≥98%

Formulation(Request formulation change)

A crystalline solid

Solubility(Learn about Variance in Solubility)

DMF: 2 mg/ml
Ethanol: 10 mg/ml
Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/ml

λ_max

251 nm

SMILES

CC1=C2[C@](CC[C@]13O[C@@](C[C@H](C)CN4)([H])[C@]4([H])[C@H]3C)([H])[C@]5([H])CC=C6C[C@@H](O)CC[C@]6(C)[C@@]5([H])C2=O

InChi Code

InChI=1S/C27H39NO3/c1-14-11-21-24(28-13-14)16(3)27(31-21)10-8-19-20-6-5-17-12-18(29)7-9-26(17,4)23(20)25(30)22(19)15(27)2/h5,14,16,18-21,23-24,28-29H,6-13H2,1-4H3/t14-,16+,18-,19-,20-,21+,23+,24-,26-,27-/m0/s1

InChi Key

CLEXYFLHGFJONT-DNMILWOZSA-N

Shipping & Storage Information

Storage

-20°C

Shipping

Room Temperature in continental US; may vary elsewhere

Stability

≥ 4 years

Specifications

More Information
SKU	CAYM-11723-10
Supplier Part Number	11723-10
UM	UNIT
UNSPSC	12352200
Manufacturer	Cayman
MSDS URL	https://www.caymanchem.com/msdss/11723m.pdf
Temperature	-20
Refrigerated-Frozen	Refrigerated
CountryOfOrigin	CN
ProductLine	CAYM
Qty	10
MinOrderQty	1
Weight	7.00
Lead Time	2 Business Days
Hazardous	Y
CAS Number	469-59-0

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Cayman Jervine; Purity- Greater Than Or Equal To 98%; Size- 10 Mg

Product Description

Technical Information

Shipping & Storage Information

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