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Cayman Prostaglandin E1 Ethanolamide; Purity- Greater Than Or Equ
Cayman Prostaglandin E1 Ethanolamide; Purity- Greater Than Or Equal To 98%; Size- 1 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$64.00
Your Price
$64.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-13012-1 |
| MFG.PART: | 13012-1 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
TGR-1202 is an inhibitor of PI3K p110δ (IC50 = 22 nM). It is selective for p110δ over p110α, p110β, and p110γ (IC50s = >10,000, 1,116, and 1,065 nM, respectively)., TGR-1202 induces apoptosis in patient-derived chronic lymphocytic leukemia lymphocytes when used at concentrations ranging from 0.1 to 25.6 µM. In vivo, TGR-1202 (150 mg/kg) reduces tumor growth in a MOLT-4 T cell acute lymphoblastic leukemia (T-ALL) mouse xenograft model.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2-[(1S)-1-[4-
CAS Number
1532533-67-7
Synonyms
- RP 5264
- Umbralisib
Molecular Formula
C31H24F3N5O3
Formula Weight
571.6
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 1 mg/ml
- DMSO: 1 mg/ml
λmax
232, 291 nm
SMILES
C[C@@H](C1=C(C2=CC(F)=CC=C2)C(C3=CC(F)=CC=C3O1)=O)N4N=C(C5=CC=C(OC(C)C)C(F)=C5)C6=C(N)N=CN=C46
InChi Code
InChI=1S/C31H24F3N5O3/c1-15(2)41-24-9-7-18(12-22(24)34)27-26-30(35)36-14-37-31(26)39(38-27)16(3)29-25(17-5-4-6-19(32)11-17)28(40)21-13-20(33)8-10-23(21)42-29/h4-16H,1-3H3,(H2,35,36,37)/t16-/m0/s1
InChi Key
IUVCFHHAEHNCFT-INIZCTEOSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-13012-1 |
|---|---|
| Supplier Part Number | 13012-1 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/13012m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | US |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | Y |
| CAS Number | 210976-81-1 |