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Cayman Oxaliplatin; Purity- Greater Than Or Equal To 98%; Size- 5
NETA PART: | CAYM-13106-50 |
MFG.PART: | 13106-50 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Oxaliplatin is a platinum-containing DNA-crosslinking agent.1 It induces the formation of DNA inter- and intrastrand crosslinks and DNA-protein crosslinks, inhibits DNA and RNA synthesis, and induces apoptosis in cancer cells. Oxaliplatin is cytotoxic to cisplatin-sensitive A2780(1A9) and KB-3-1 cells and cisplatin-resistant A2780-E(80) and KB-CP20 cells (IC50s = 0.12, 0.39, 4.7, and 2.7 µM, respectively).2 It reduces tumor growth in an HCCLM3 mouse xenograft model when administered at doses of 5 or 10 mg/kg once per week.3 Formulations containing oxaliplatin have been used in the treatment of advanced colorectal cancer and as an adjuvant in stage III colon cancer.
WARNING This product is not for human or veterinary use.
Technical Information
- Lipoxal
- NSC 266046
- RP 54780
- PBS (pH 7.2): 0.01 mg/ml
Shipping & Storage Information
SKU | CAYM-13106-50 |
---|---|
Supplier Part Number | 13106-50 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/13106m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | GB |
ProductLine | CAYM |
Qty | 50 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 61825-94-3 |