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Cayman N-Acetyl-D-Glucosamine; Purity- Greater Than Or Equal To 9
Cayman N-Acetyl-D-Glucosamine; Purity- Greater Than Or Equal To 98%; Size- 500 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$14.00
Your Price
$14.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-13136-500 |
| MFG.PART: | 13136-500 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA; Item No. ) and docosahexaenoic acid (DHA; Item No. ). In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response back to a non-inflamed state. Resolvin D2 (RvD2) is produced physiologically from the sequential oxygenation of DHA by 15- and 5-lipoxygenase and functions to dampen excessive neutrophil trafficking to sites of inflammation. It reduces zymosan-stimulated PMN infiltration by 70% at doses as low as 10 pg per mouse and significantly reduces PAF-stimulated leukocyte adherence and emigration at 1 nM. Also, by stimulating nitric oxide production, RvD2 dose dependently decreases leukocyte-endothelial interactions. In a mouse model of sepsis, RvD2 reduces leukocyte and PMN infiltration, decreases production of pro-inflammatory cytokines, and promotes phagocyte-mediated bacterial clearance.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
7S,16R,17S-
CAS Number
810668-37-2
Synonyms
- 7(S),16(R),17(S)-
Resolvin D2 - RvD2
Molecular Formula
C22H32O5
Formula Weight
376.5
Purity
≥95%
Formulation
A solution in ethanol
Solubility
- DMF: 50 mg/ml
- Ethanol: 50 mg/ml
- PBS (pH 7.2): .05 mg/ml
λmax
289, 302, 317 nm
SMILES
CC/C=C\C[C@H](O)[C@H](O)/C=C/C=C/C=C\C=C\[C@@H](O)C/C=C\CCC(O)=O
InChi Code
InChI=1S/C22H32O5/c1-2-3-9-16-20(24)21(25)17-12-7-5-4-6-10-14-19(23)15-11-8-13-18-22(26)27/h3-12,14,17,19-21,23-25H,2,13,15-16,18H2,1H3,(H,26,27)/b6-4-,7-5+,9-3-,11-8-,14-10+,17-12+/t19-,20+,21-/m1/s1
InChi Key
IKFAUGXNBOBQDM-XFMPMKITSA-N
Shipping & Storage Information
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
Stability
≥ 1 year
| SKU | CAYM-13136-500 |
|---|---|
| Supplier Part Number | 13136-500 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/13136m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | US |
| ProductLine | CAYM |
| Qty | 500 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 7512-17-6 |