Cayman Celastramycin A; Purity- Greater Than Or Equal To 97%; Siz

D-Cycloserine is an NMDA receptor (NMDAR) partial agonist with antibiotic activity. It selectively binds to the glycine binding site (K_i = 2.33 μM) over the glutamate binding site (K_i = >100 μM). D-Cycloserine modulates memory in a T-maze footshock test in CD-1 mice with optimal memory retention at doses of 10-30 mg/kg. Administration of D-cycloserine (20-40 mg/kg) improves memory retention in ‘senescence-accelerated’ mice which exhibit impaired learning and memory. D-Cycloserine inhibits L-alanine racemase and D-alanine:D-alanine ligase, enzymes essential to peptidoglycan synthesis and bacterial cell wall formation. Formulations containing D-cycloserine have been used as second-line agents to treat drug resistant tuberculosis.

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