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Cayman Jnj-5207787; Purity- Greater Than Or Equal To 98%; Size- 1
NETA PART: | CAYM-13947-10 |
MFG.PART: | 13947-10 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Oleandrin is a glycoside that has been found in N. oleander and has diverse biological activities.,,, It inhibits NF-κB activation induced by hydrogen peroxide, LPS, okadaic acid (Item No. ), ceramide, or TNF in U937 cells when used at a concentration of 1 µg/ml. Oleandrin inhibits transmissible gastroenteritis virus (TGEV) replication without inducing cytotoxicity in swine testis cells (IC50 = 147 nM). It reduces pyramidal neuron cell death induced by oxygen-glucose deprivation (OGD) in cultured rat brain explant slices. Oleandrin reduces viability and inhibits migration of U87MG, A172, U251, and GBM19 glioma cells. In vivo, oleandrin (0.3 mg/kg) reduces tumor size and increases survival in U78MG, GL261, and U251 glioma mouse xenograft models.
WARNING This product is not for human or veterinary use.
Technical Information
- Folinerin
- Neriolin
- DMF: 15 mg/ml
- DMF:PBS (pH 7.2) (1:4): 0.2 mg/ml
- DMSO: 10 mg/ml
- Ethanol: 5 mg/ml
Shipping & Storage Information
SKU | CAYM-13947-10 |
---|---|
Supplier Part Number | 13947-10 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/13947m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 10 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 683746-68-1 |