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Cayman Jwh 198; Purity- Greater Than Or Equal To 98%; Size- 10 Mg
Cayman Jwh 198; Purity- Greater Than Or Equal To 98%; Size- 10 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$131.00
Your Price
$131.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-13981-10 |
| MFG.PART: | 13981-10 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
UK 356618 is an inhibitor of matrix metalloproteinase-3 (MMP-3; IC50 = 5.9 nM). It is selective for MMP-3 over MMP-1, -2, -9, -13, and -14 (IC50s = 51, 1.79, 0.84, 0.073, and 1.9 µM, respectively). UK 356618 (73 nM) inhibits IL-6-induced migration of NCI H446 small cell lung cancer (SCLC) cells in vitro. It reduces hyperglycemia-exacerbated increases in brain edema and hemorrhagic transformation in the cortex and striatum in a rat model of ischemia-reperfusion injury induced by middle cerebral artery occlusion (MCAO) when administered intravenously at a dose of 15 mg/kg.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(2R)-N1-[(1S)-
CAS Number
230961-08-7
Molecular Formula
C34H43N3O4
Formula Weight
557.7
Purity
≥98%
Formulation
A solid
Solubility
- DMSO: 50 mg/ml
SMILES
CC1=C(C2=CC=CC=C2)C=CC(CCC[C@H](CC(NO)=O)C(N[C@@H](C(C)(C)C)C(N[C@@H](C3=CC=CC=C3)C)=O)=O)=C1
InChi Code
InChI=1S/C34H43N3O4/c1-23-21-25(19-20-29(23)27-16-10-7-11-17-27)13-12-18-28(22-30(38)37-41)32(39)36-31(34(3,4)5)33(40)35-24(2)26-14-8-6-9-15-26/h6-11,14-17,19-21,24,28,31,41H,12-13,18,22H2,1-5H3,(H,35,40)(H,36,39)(H,37,38)/t24-,28-,31-/m1/s1
InChi Key
JJHRUUKMPWUYIB-HVOSOHGQSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-13981-10 |
|---|---|
| Supplier Part Number | 13981-10 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/13981m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | US |
| ProductLine | CAYM |
| Qty | 10 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 166599-76-4 |