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Cayman Mdl 72527 (Hydrochloride); Purity- Greater Than Or Equal T
Cayman Mdl 72527 (Hydrochloride); Purity- Greater Than Or Equal To 95%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$116.00
Your Price
$116.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-13996-5 |
| MFG.PART: | 13996-5 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
LH1306 is an inhibitor of the interaction between programmed cell death 1 (PD-1) and its ligand PD-L1 that has an IC50 value of 25 nM in a homologous time-resolved fluorescence (HTRF) assay. It increases the activation of Jurkat cells expressing PD-1 in co-culture with U2OS or CHO cells expressing PD-L1 (EC50s = 334 and 4,214 nM, respectively, in reporter assays).
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N,N′-[(2,2′-
CAS Number
2182653-84-3
Molecular Formula
C38H48N6O6
Formula Weight
684.8
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMF: 1mg/mL
- DMSO: 0.25mg/mL
λmax
283 nm
SMILES
CC1=C(COC2=CC=C(CNCCNC(C)=O)C(OC)=N2)C=CC=C1C3=C(C)C(COC4=NC(OC)=C(CNCCNC(C)=O)C=C4)=CC=C3
InChi Code
InChI=1S/C38H48N6O6/c1-25-31(23-49-35-15-13-29(37(43-35)47-5)21-39-17-19-41-27(3)45)9-7-11-33(25)34-12-8-10-32(26(34)2)24-50-36-16-14-30(38(44-36)48-6)22-40-18-20-42-28(4)46/h7-16,39-40H,17-24H2,1-6H3,(H,41,45)(H,42,46)
InChi Key
ZNRITEYTYHQVTF-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 2 years
| SKU | CAYM-13996-5 |
|---|---|
| Supplier Part Number | 13996-5 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/13996m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | CN |
| ProductLine | CAYM |
| Qty | 5 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 93565-01-6 |