Cayman Leupeptin (Hemisulfate)

Cayman Leupeptin (Hemisulfate); N-Acetyl-L-Leucyl-N-[4-[(Aminoiminomethyl)Amino]-1s-Formylbutyl]-L-Leucinamide, Hemisulfate; Purity- Greater Than Or Equal To 90%; Size- 100 Mg . Leupeptin is a reversible inhibitor of cysteine, serine and threonine proteases that is produced naturally by Streptomyces. It has been reported to inhibit cathepsin B (Ki = 6 nM), calpain (Ki = 10 nM), trypsin (Ki = 35 nM), plasmin (Ki = 3.4 uM) and kallikrein (Ki = 19 uM) and has no effect against chymotrypsin, elastase, renin or pepsin. Leupeptin has been shown to be protective of auditory hair cells exposed to disruptive noise or ototoxic aminoglycoside-type anti-biotics. It is also widely used as a protein purification tool to prevent proteases present in tissue samples from degrading the protein of interest - CAYM (Additional S&H Or Hazmat Fees May Apply)