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Cayman Chrysomycin A; Purity- Greater Than Or Equal To 98%; Size-
Cayman Chrysomycin A; Purity- Greater Than Or Equal To 98%; Size- 1 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$359.00
Your Price
$359.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-14188-1 |
| MFG.PART: | 14188-1 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
DL-threo-PPMP is a ceramide analog and an inhibitor of glucosylceramide synthase. It inhibits glucosylceramide synthase by 70, 41, and 62% in MDCK cell homogenates, mouse liver microsomes, and mouse brain homogenates, respectively, when used at a concentration of 20 µM. DL-threo-PPMP also inhibits sphingomyelin synthase activity in erythrocytes infected with P. falciparum and inhibits late ring-stage P. falciparum growth (IC50 = 0.85 µM). It reduces Akt and ribosomal protein S6 phosphorylation in HEK293 cells and increases autophagy flux in primary mouse neurons. [Matreya, LLC. Catalog No. 1720]
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
rel-N-[(1R,2R)-2-hydroxy-1-(4-morpholinylmethyl)-2-phenylethyl]-hexadecanamide, monohydrochloride
CAS Number
139974-41-7
Synonyms
- DL-threo-1-Phenyl-2-palmitoylamino-3-morpholino-1-propanol
Molecular Formula
C29H50N2O3 • HCl
Formula Weight
511.2
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 5 mg/ml
- DMSO: 20 mg/ml
- Ethanol: 10 mg/ml
SMILES
O=C(CCCCCCCCCCCCCCC)N[C@H](CN1CCOCC1)[C@H](O)C2=CC=CC=C2.Cl
InChi Code
InChI=1S/C29H50N2O3.ClH/c1-2-3-4-5-6-7-8-9-10-11-12-13-17-20-28(32)30-27(25-31-21-23-34-24-22-31)29(33)26-18-15-14-16-19-26;/h14-16,18-19,27,29,33H,2-13,17,20-25H2,1H3,(H,30,32);1H/t27-,29-;/m1./s1
InChi Key
ORVAUBQYJOFWFY-ZHESDOBJSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-14188-1 |
|---|---|
| Supplier Part Number | 14188-1 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/14188m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | CH |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 82196-88-1 |