Cayman Tetrahydromagnolol; Purity- Greater Than Or Equal To 98%;

Tetrahydromagnolol is an agonist of cannabinoid (CB) receptors, an antagonist of GPR55 (K_B = 13.3 µM in a β-arrestin translocation assay), and a major metabolite of magnolol (Item No. ). Tetrahydromagnolol binds to the CB₁ and CB₂ receptors (K_is = 2.26 and 0.416 µM, respectively, for the human receptor) and inhibits forskolin-induced cAMP accumulation (EC₅₀ = 9.01 and 0.17 µM, respectively, in CHO cells expressing the human receptors). Tetrahydromagnolol reduces melanin biosynthesis, as well as decreases tyrosinase protein levels by inhibiting tyrosinase maturation and increasing the rate of its degradation.

WARNING This product is not for human or veterinary use.