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Cayman Luotonin A; Purity- Greater Than Or Equal To 98%; Size- 10
Cayman Luotonin A; Purity- Greater Than Or Equal To 98%; Size- 10 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$160.65
Your Price
$160.65
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-14253-10 |
| MFG.PART: | 14253-10 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
Oleandrin is a glycoside that has been found in N. oleander and has diverse biological activities.,,, It inhibits NF-κB activation induced by hydrogen peroxide, LPS, okadaic acid (Item No. ), ceramide, or TNF in U937 cells when used at a concentration of 1 µg/ml. Oleandrin inhibits transmissible gastroenteritis virus (TGEV) replication without inducing cytotoxicity in swine testis cells (IC50 = 147 nM). It reduces pyramidal neuron cell death induced by oxygen-glucose deprivation (OGD) in cultured rat brain explant slices. Oleandrin reduces viability and inhibits migration of U87MG, A172, U251, and GBM19 glioma cells. In vivo, oleandrin (0.3 mg/kg) reduces tumor size and increases survival in U78MG, GL261, and U251 glioma mouse xenograft models.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(3β,5β,16β)-
CAS Number
465-16-7
Synonyms
- Folinerin
- Neriolin
Molecular Formula
C32H48O9
Formula Weight
576.7
Purity
≥98%
Formulation
A solid
Solubility
- DMF: 15 mg/ml
- DMF:PBS (pH 7.2) (1:4): 0.2 mg/ml
- DMSO: 10 mg/ml
- Ethanol: 5 mg/ml
SMILES
CO[C@@H](C1)[C@@H](O)[C@H](C)O[C@H]1O[C@H](C2)CC[C@@]3(C)[C@]2([H])CC[C@]4([H])[C@]3([H])CC[C@@]5(C)[C@]4(O)C[C@H](OC(C)=O)[C@]5([H])C6=CC(OC6)=O
InChi Code
InChI=1S/C32H48O9/c1-17-29(35)24(37-5)14-27(39-17)41-21-8-10-30(3)20(13-21)6-7-23-22(30)9-11-31(4)28(19-12-26(34)38-16-19)25(40-18(2)33)15-32(23,31)36/h12,17,20-25,27-29,35-36H,6-11,13-16H2,1-5H3/t17-,20+,21-,22-,23+,24-,25-,27-,28-,29-,30-,31+,32-/m0/s1
InChi Key
JLPDBLFIVFSOCC-XYXFTTADSA-N
Origin
Plant/Nerium oleander
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-14253-10 |
|---|---|
| Supplier Part Number | 14253-10 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/14253m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | US |
| ProductLine | CAYM |
| Qty | 10 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | Y |
| CAS Number | 205989-12-4 |