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Cayman 16,16-Dimethyl Prostaglandin E2 P-(P-Acetamidobenzamido) P
Cayman 16,16-Dimethyl Prostaglandin E2 P-(P-Acetamidobenzamido) Phenyl Ester; Purity- Greater Than Or Equal To 98%; Size- 10 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$1,053.00
Your Price
$1,053.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-14753-10 |
| MFG.PART: | 14753-10 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
Nedaplatin is a derivative of cisplatin (Item No. ) with anticancer activity. Nedaplatin undergoes spontaneous hydrolysis to form platinum complexes that cross-link DNA resulting in apoptosis and cell death., It inhibits the growth of human NUGC-4 gastric and KSE-1 esophageal squamous carcinoma cells (IC50s = 4.6 and 3.4 μM, respectively) and inhibits S to G2 and G2/M to G1 cell cycle progression. Nedaplatin (44 mg/kg) decreases tumor volume and increases survival in a Lewis lung carcinoma syngeneic mouse model. Nedaplatin (40 mg/kg) also decreases tumor volume in an HNC-3 head and neck cancer mouse xenograft model. It exhibits reduced nephrotoxicity in rats compared with cisplatin.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(SP-4-3)-
CAS Number
95734-82-0
Synonyms
- NSC 375101
Molecular Formula
C2H8N2O3Pt
Formula Weight
303.2
Purity
≥95%
Formulation
A crystalline solid
Solubility
- Water: *soluble
SMILES
[NH3][Pt+2]([O-]C1=O)([O-]C1)[NH3]
InChi Code
InChI=1S/C2H3O3.2H3N.Pt/c3-1-2(4)5;;;/h1H2,(H,4,5);2*1H3;/q-1;;;+2/p-1
InChi Key
GYAVMUDJCHAASE-UHFFFAOYSA-M
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 2 years
| SKU | CAYM-14753-10 |
|---|---|
| Supplier Part Number | 14753-10 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/14753m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | US |
| ProductLine | CAYM |
| Qty | 10 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 62873-55-6 |