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Cayman Cucurbitacin E; Purity- Greater Than Or Equal To 98%; Size
Cayman Cucurbitacin E; Purity- Greater Than Or Equal To 98%; Size- 10 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$302.00
Your Price
$302.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-14821-10 |
| MFG.PART: | 14821-10 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
Cucurbitacin E is a plant-derived triterpene that has diverse biological activities. At a concentration of 10 pM, it reduces MPP+-induced death of neuronal PC12 cells through inhibition of autophagy in vitro.1 Cucurbitacin E inhibits growth of T24 bladder, MDA-MB-468 and MCF-7 breast, PC3 prostate, and colorectal cancer cell lines (IC50s = 50-1,000 nM) through induction of G2/M arrest and apoptosis.2,3,4 It increases bilirubin binding to human serum albumin (HSA) in human plasma in a dose-dependent manner.5 Cucurbitacin E also inhibits depolymerization of actin filaments isolated from rabbit skeletal muscle actin and in HeLa cells.6
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(9β,10α,16α,
CAS Number
18444-66-1
Synonyms
- NSC 106399
- NSC 521775
Molecular Formula
C32H44O8
Formula Weight
556.7
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 30 mg/ml
- DMSO: 30 mg/ml
- Ethanol: 30 mg/ml
- Ethanol:PBS (pH 7.2) (1:4): 0.2 mg/ml
λmax
234 nm
SMILES
OC(C(C1(C)C)=O)=C[C@]2([H])C1=CC[C@]([C@@](C[C@@H](O)[C@]3([H])[C@](O)(C)C(/C=C/C(C)(C)OC(C)=O)=O)(C)[C@]3(C)C4)([H])[C@@]2(C)C4=O
InChi Code
InChI=1S/C32H44O8/c1-17(33)40-27(2,3)13-12-23(36)32(9,39)25-21(35)15-29(6)22-11-10-18-19(14-20(34)26(38)28(18,4)5)31(22,8)24(37)16-30(25,29)7/h10,12-14,19,21-22,25,34-35,39H,11,15-16H2,1-9H3/b13-12+/t19-,21-,22+,25+,29+,30-,31+,32+/m1/s1
InChi Key
NDYMQXYDSVBNLL-MUYMLXPFSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-14821-10 |
|---|---|
| Supplier Part Number | 14821-10 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/14821m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | CN |
| ProductLine | CAYM |
| Qty | 10 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 18444-66-1 |