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Cayman 25i-Nboh (Hydrochloride); Purity- Greater Than Or Equal To
Cayman 25i-Nboh (Hydrochloride); Purity- Greater Than Or Equal To 95%; Size- 1 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$70.00
Your Price
$70.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-14909-1 |
| MFG.PART: | 14909-1 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
Neotuberostemonine is an alkaloid originally isolated from S. tuberosa that has diverse biological activities.,, It inhibits LPS-induced increases in inducible nitric oxide synthase (iNOS) protein levels and NO production in RAW 264.7 cells when used at a concentration of 100 µM. Neotuberostemonine (50 µM) inhibits RANKL-induced osteoclast differentiation of RAW 264.7 cells. It reduces the citric acid-induced cough reflex in conscious guinea pigs when administered at a dose of 133 µmol/kg. Neotuberostemonine (40 mg/kg) inhibits pulmonary collagen deposition and fibrosis, as well as bronchoalveolar lavage fluid (BALF) monocyte and lymphocyte infiltration in a mouse model of bleomycin-induced pulmonary fibrosis.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(2S,7aR,8R,
CAS Number
143120-46-1
Synonyms
- (+)-Neotuberostemonine
- Tuberostemonine LG
Molecular Formula
C22H33NO4
Formula Weight
375.5
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMSO: 10 mM
SMILES
O=C(O1)[C@@H](C)[C@]2([H])[C@@]1([H])[C@H](CC)[C@]3([H])[C@]4([H])[C@@]2([H])C[C@]([C@@]5([H])OC([C@@H](C)C5)=O)([H])N4CCCC3
InChi Code
InChI=1S/C22H33NO4/c1-4-13-14-7-5-6-8-23-16(17-9-11(2)21(24)26-17)10-15(19(14)23)18-12(3)22(25)27-20(13)18/h11-20H,4-10H2,1-3H3/t11-,12-,13+,14+,15-,16-,17-,18-,19+,20+/m0/s1
InChi Key
GYOGHROCTSEKDY-UEIGSNQUSA-N
Origin
Plant/Stemona japonica
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-14909-1 |
|---|---|
| Supplier Part Number | 14909-1 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/14909m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | US |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 1539266-12-0 |