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Cayman Glutathione Ethyl Ester; Purity- Greater Than Or Equal To
NETA PART: | CAYM-14953-50 |
MFG.PART: | 14953-50 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Glutathione (GSH) ethyl ester is a cell-permeable derivative of GSH (Item No. 10007461), a nucleophilic co-substrate to glutathione transferases.1 It increases mitochondrial GSH levels in C38 and IB3-1 epithelial lung cystic fibrosis cells when used at a concentration of 10 mM.2 GSH ethyl ester (10 mM) decreases reactive oxygen species (ROS) levels and TNF-α-induced IL-8 secretion in IB3-1 cells. GSH ethyl increases mitochondrial complex I, also known as NADH dehydrogenase, function and reduces depolarization of the mitochondrial membrane potential in IB3-1 when used at concentrations of 10 mM and 1mM, respectively. It decreases lipid oxidation and ferroptosis in cystine-deficient PANC-1, AsPC-1, BxPC-3, and S2-013 pancreatic cancer cells.3 GSH ethyl ester increases the viability of irradiated human lymphoid cells when used at a concentration of 5 mM.1
WARNING This product is not for human or veterinary use.
Technical Information
- GSH-EE
- GSH ethyl ester
- GSH monoethyl ester
- PBS (pH 7.2): 10 mg/ml
- Water: 20 mg/ml
Shipping & Storage Information
SKU | CAYM-14953-50 |
---|---|
Supplier Part Number | 14953-50 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/14953m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | CH |
ProductLine | CAYM |
Qty | 50 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 92614-59-0 |