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Cayman Prostaglandin F1 Alpha Alcohol; Purity- Greater Than Or Eq
Cayman Prostaglandin F1 Alpha Alcohol; Purity- Greater Than Or Equal To 99%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$241.00
Your Price
$241.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-15020-5 |
| MFG.PART: | 15020-5 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
CC-223 is a potent inhibitor of mTOR (IC50 = 16 nM) that shows selectivity for mTOR over a panel of 246 other kinases. It blocks signaling through both mTORC1 and mTORC2, inhibiting the phosphorylation of S6RP, 4EBP1, and Akt(S473) in cellular systems. CC-223 inhibits growth and induces apoptosis in hematologic and solid tumor cell lines in vitro, and it exhibits dose-dependent tumor growth inhibition in multiple solid tumor xenografts in vivo.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
3,4-dihydro-7
CAS Number
1228013-30-6
Molecular Formula
C21H27N5O3
Formula Weight
397.5
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/mL
- DMF:PBS(pH 7.2)(1:1): 0.5 mg/mL
- DMSO: 25 mg/mL
- Ethanol: 20 mg/mL
λmax
219, 236, 313, 355 nm
SMILES
CO[C@@H]1CC[C@@H](N2C(CN=C3C2=NC(C4=CN=C(C(O)(C)C)C=C4)=CN3)=O)CC1
InChi Code
InChI=1S/C21H27N5O3/c1-21(2,28)17-9-4-13(10-22-17)16-11-23-19-20(25-16)26(18(27)12-24-19)14-5-7-15(29-3)8-6-14/h4,9-11,14-15,28H,5-8,12H2,1-3H3,(H,23,24)/t14-,15-
InChi Key
UFKLYTOEMRFKAD-SHTZXODSSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-15020-5 |
|---|---|
| Supplier Part Number | 15020-5 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/15020m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | US |
| ProductLine | CAYM |
| Qty | 5 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 13487-47-3 |