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Cayman Ursodeoxycholic Acid (Sodium Salt); Purity- Greater Than O
Cayman Ursodeoxycholic Acid (Sodium Salt); Purity- Greater Than Or Equal To 98%; Size- 500 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$129.00
Your Price
$129.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-15121-500 |
| MFG.PART: | 15121-500 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
Zatebradine is a bradycardic compound that blocks hyperpolarization-activated inward current (If) through cyclic nucleotide-gated cation (HCN) channels in sinoatrial node cells (IC50s = 1.83, 2.21, 1.9, and 1.88 µM, respectively for HCN1-4 in vitro)., Additionally, it can block voltage-gated outward K+ (IK) currents and related neuronal hyperpolarization-activated inward current (Ih) channels, but exhibits little or no activity for L-type Ca2+ (ICa) currents., When assessed through telemetric ECG recording in mice, zatebradine reduced heart rate from 600 to 200 beats per minute with an ED50 value of 1.8 mg/kg and induced increasing arrhythmia at concentrations >10 mg/kg.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
3-[3-[[2-(3,4-
CAS Number
91940-87-3
Synonyms
- UL-FS 49
Molecular Formula
C26H36N2O5 • HCl
Formula Weight
493.0
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMF: 25 mg/ml
- DMSO: 20 mg/ml
- Ethanol: 1 mg/ml
- PBS (pH 7.2): 10 mg/ml
λmax
280 nm
SMILES
COC1=CC(CCN(C)CCCN2C(CC(C=C(OC)C(OC)=C3)=C3CC2)=O)=CC=C1OC.Cl
InChi Code
InChI=1S/C26H36N2O5.ClH/c1-27(13-9-19-7-8-22(30-2)23(15-19)31-3)11-6-12-28-14-10-20-16-24(32-4)25(33-5)17-21(20)18-26(28)29;/h7-8,15-17H,6,9-14,18H2,1-5H3;1H
InChi Key
ZRNKXJHEQKMWCH-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-15121-500 |
|---|---|
| Supplier Part Number | 15121-500 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/15121m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | CN |
| ProductLine | CAYM |
| Qty | 500 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 2898-95-5 |