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Cayman Sb 204990; Purity- Greater Than Or Equal To 95%; Size- 10
Cayman Sb 204990; Purity- Greater Than Or Equal To 95%; Size- 10 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$198.00
Your Price
$198.00
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | CAYM-15245-10 |
MFG.PART: | 15245-10 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
MMP-8 Inhibitor I is a selective inhibitor of the neutrophil collagenase matrix metalloproteinase-8 (MMP-8) with an IC50 value of 4 nM. This inhibitor does not target the activities of other MMPs in vitro., MMP-8 cleaves interstitial collagens and has exhibited activity in atherosclerotic plaques, angiogenesis, and stem cell mobilization. Additionally, MMP-8 expression is observed in normal mammary epithelial cells, whereas a loss of expression is observed in human ductal carcinoma in situ and the deletion of MMP-8 accelerates tumor onset in a mouse model of aggressive breast cancer.,
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(3R)-1,2,3,4- tetrahydro-N- hydroxy-2-[(4 -methoxyphen yl)sulfonyl]- 3-isoquinoline carboxamide
CAS Number
236403-25-1
Synonyms
- Matrix Metalloproteinase-8 Inhibitor I
Molecular Formula
C17H18N2O5S
Formula Weight
362.4
Purity
≥95%
Formulation
A solid
Solubility
- DMSO: 200 mg/ml
SMILES
O=C(NO)[C@@H]1N(S(C2=CC=C(OC)C=C2)(=O)=O)CC3=CC=CC=C3C1
InChi Code
InChI=1S/C17H18N2O5S/c1-24-14-6-8-15(9-7-14)25(22,23)19-11-13-5-3-2-4-12(13)10-16(19)17(20)18-21/h2-9,16,21H,10-11H2,1H3,(H,18,20)/t16-/m1/s1
InChi Key
PPELJLBDXLMTEW-MRXNPFEDSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
SKU | CAYM-15245-10 |
---|---|
Supplier Part Number | 15245-10 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/15245m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 10 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 154566-12-8 |