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Cayman Ck 869; Purity- Greater Than Or Equal To 98%; Size- 10 Mg
Cayman Ck 869; Purity- Greater Than Or Equal To 98%; Size- 10 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$186.00
Your Price
$186.00
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | CAYM-15251-10 |
MFG.PART: | 15251-10 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
IPI-145 is a potent inhibitor of the phosphoinositide 3-kinase (PI3K) isoforms PI3Kγ and PI3Kδ (IC50s = 0.24 and 50 nM, respectively). It is orally bioavailable and selective. As PI3Kγ and PI3Kδ are preferentially expressed in immune cells, IPI-145 has profound effects in collagen-induced and adjuvant-induced arthritis, ovalbumin-induced asthma, and systemic lupus erythematosus animal models., It also has potential applications in immunotherapy and in certain cancers.,
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
8-chloro-2-phenyl-3-[(1S)-1-(9H-purin-6-ylamino)ethyl]-1(2H)-isoquinolinone
CAS Number
1201438-56-3
Synonyms
- Duvelisib
- INK1197
Molecular Formula
C22H17ClN6O
Formula Weight
416.9
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 10 mg/ml
- DMSO: 10 mg/ml
- DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml
- Ethanol: 10 mg/ml
λmax
213, 239, 270, 344 nm
SMILES
C[C@@H](C1=CC(C=CC=C2Cl)=C2C(N1C3=CC=CC=C3)=O)NC4=C5C(N=CN5)=NC=N4
InChi Code
InChI=1S/C22H17ClN6O/c1-13(28-21-19-20(25-11-24-19)26-12-27-21)17-10-14-6-5-9-16(23)18(14)22(30)29(17)15-7-3-2-4-8-15/h2-13H,1H3,(H2,24,25,26,27,28)/t13-/m0/s1
InChi Key
SJVQHLPISAIATJ-ZDUSSCGKSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
SKU | CAYM-15251-10 |
---|---|
Supplier Part Number | 15251-10 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/15251m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 10 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | Y |
CAS Number | 388592-44-7 |