We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Share this :
Print
Cayman 5-Hydroxy Dmt (Hydrochloride) (Exempt Preparation); Purity
Cayman 5-Hydroxy Dmt (Hydrochloride) (Exempt Preparation); Purity- Greater Than Or Equal To 98%; Size- 1 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$62.00
Your Price
$62.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-15693-1 |
| MFG.PART: | 15693-1 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
Histone H3K27Me2 (21-44)-GK-biotin is a peptide fragment of histone H3 that corresponds to amino acid residues 22-45 of the human histone H3.1 and 3.2 sequences. It is dimethylated at lysine 27 and biotinylated via a C-terminal GK linker. Dimethylation of H3K27 is present on large chromatin domains across approximately 70% of total histone H3 and prevents firing of non-cell type-specific enhancers. H3K27Me2 accumulates in gene bodies of genes with low levels of expression in mouse embryonic stem cells. Histone H3K27Me2 (21-44)-GK-biotin has been used as a positive control in a high-throughput screen for inhibitors of the histone demethylase jumonji AT-rich interactive domain 1B (JARID1B).
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
L-alanyl-L-
Synonyms
- ATKAAR-K(Me2)-SAPATGGVKKPHRYRPG-GK(Biotin)
- Histone H3 (21-24) (Lys27me2)-GK(Biotin)
- [Lys(Me2)27]-Histone H3 (21-44)-GK(Biotin) (trifluoroacetate salt)
Molecular Formula
C129H218N44O33S • XCF3COOH
Formula Weight
2945.5
Purity
≥95%
Formulation
A solid
Solubility
- Water: 1 mg/ml
SMILES
O=C(O)C(F)(F)F.O=C(NCCCC[C@@H](C(O)=O)NC(CNC(CNC([C@@H]1CCCN1C([C@H](CCCNC(N)=N)NC([C@@H](NC([C@H](CCCNC(N)=N)NC([C@@H](NC([C@@H]2CCCN2C([C@H](CCCCN)NC([C@H](CCCCN)NC([C@H](C(C)C)NC(CNC(CNC([C@@]([C@@H](C)O)([H])NC([C@@H](NC([C@@H]3CCCN3C([C@@H](NC([C@H](CO)NC([C@H](CCCCN(C)C)NC([C@H](CCCNC(N)=N)NC([C@@H](NC([C@@H](NC([C@H](CCCCN)NC([C@@]([C@@H](C)O)([H])NC([C@@H](N[H])C)=O)=O)=O)C)=O)C)=O)=O)=O)=O)C)=O)=O)C)=O)=O)=O)=O)=O)=O)=O)=O)CC4=CN=CN4)=O)=O)CC5=CC=C(O)C=C5)=O)=O)=O)=O)=O)CCCC[C@@H]6SC[C@@](N7)([H])[C@]6([H])NC7=O
InChi Code
InChI=1S/C129H218N44O33S.C2HF3O2/c1-68(2)100(166-99(182)64-146-97(180)62-148-119(198)101(74(8)175)168-107(186)72(6)152-117(196)92-39-28-55-171(92)122(201)73(7)153-115(194)89(65-174)164-112(191)80(32-18-23-54-170(10)11)156-109(188)82(35-24-51-142-126(134)135)155-106(185)71(5)150-105(184)70(4)151-108(187)79(30-14-19-47-130)159-121(200)102(75(9)176)167-104(183)69(3)133)120(199)158-81(31-15-20-48-131)110(189)160-84(33-16-21-49-132)123(202)173-57-29-40-93(173)118(197)163-88(59-77-60-140-67-149-77)114(193)157-83(36-25-52-143-127(136)137)111(190)162-87(58-76-43-45-78(177)46-44-76)113(192)161-85(37-26-53-144-128(138)139)124(203)172-56-27-38-91(172)116(195)147-61-96(179)145-63-98(181)154-86(125(204)205)34-17-22-50-141-95(178)42-13-12-41-94-103-90(66-207-94)165-129(206)169-103;3-2(4,5)1(6)7/h43-46,60,67-75,79-94,100-103,174-177H,12-42,47-59,61-66,130-133H2,1-11H3,(H,140,149)(H,141,178)(H,145,179)(H,146,180)(H,147,195)(H,148,198)(H,150,184)(H,151,187)(H,152,196)(H,153,194)(H,154,181)(H,155,185)(H,156,188)(H,157,193)(H,158,199)(H,159,200)(H,160,189)(H,161,192)(H,162,190)(H,163,197)(H,164,191)(H,166,182)(H,167,183)(H,168,186)(H,204,205)(H4,134,135,142)(H4,136,137,143)(H4,138,139,144)(H2,165,169,206);(H,6,7)/t69-,70-,71-,72-,73-,74+,75+,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,100-,101-,102-,103-;/m0./s1
InChi Key
YZFIWSAVPWULPA-VUDJXMGVSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-15693-1 |
|---|---|
| Supplier Part Number | 15693-1 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/15693m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | US |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | Y |
| CAS Number | 55206-22-9 |