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Cayman 4-Methylumbelliferyl Palmitate; Purity- Greater Than Or Eq
NETA PART: | CAYM-16089-1 |
MFG.PART: | 16089-1 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
diABZI STING agonist-1 is an agonist of the stimulator of interferon genes (STING) pathway. It induces secretion of IFN-β in human peripheral blood mononuclear cells (PBMCs; EC50 = 130 nM). diABZI STING agonist-1 (2.5 mg/kg) increases serum levels of IFN-β, IL-6, TNF, and KC/GROα in wild-type, but not Sting-/-, mice. It inhibits the cytopathic effect of the common cold human coronavirus 229E (HCoV-229E) in infected MRC-5 cells (EC50 = 3 nM). diABZI STING agonist-1 also decreases the level of severe acute respiratory coronavirus 2 (SARS-CoV-2) RNA in primary human bronchial airway epithelial cells in an air-liquid interface assay. It decreases tumor volume and increases survival in a CT26 murine colorectal cancer model when administered at a dose of 3 mg/kg.
WARNING This product is not for human or veterinary use.
Technical Information
- diABZI Stimulator of Interferon Genes Agonist 1
- Diamidobenzimidazole Stimulator of Interferon Genes Agonist 1
- Diamidobenzimidazole STING Agonist 1
- Stimulator of Interferon Genes Agonist (Compound 3)
- STING Agonist (Compound 3)
- DMSO: 50 mg/ml
Shipping & Storage Information
SKU | CAYM-16089-1 |
---|---|
Supplier Part Number | 16089-1 |
UM | EA |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/16089m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 17695-48-6 |