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Cayman 4-Methylumbelliferyl Palmitate; Purity- Greater Than Or Eq
NETA PART: | CAYM-16089-100 |
MFG.PART: | 16089-100 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Cholesterol ester storage disease and Wolman disease are recessive autosomal disorders caused by a deficiency in lysosomal acid lipase (LAL), also known as cholesteryl ester hydrolase.1,2 4-Methylumbelliferyl palmitate (4-MUP) is a fluorogenic substrate for lysosomal acid lypase (LAL).3 4-MUP is cleaved by LAL to release the fluorescent moiety 4-MU. 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nM, increasing as pH decreases.4 4-MUP may also be cleaved by other acid lipases.5,6 Recent advances allow the assessment of LAL activity in very small blood volumes using 4-MUP.1,2
WARNING This product is not for human or veterinary use.
Technical Information
- 4-MUP
- 4-
MU Palmitate - Palmitoyl 4-
Methylumbelliferone
- Chloroform: 20 mg/ml
- DMF: 10 mg/ml
- DMSO: 0.1 mg/ml
Shipping & Storage Information
SKU | CAYM-16089-100 |
---|---|
Supplier Part Number | 16089-100 |
UM | EA |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/16089m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 17695-48-6 |