Cayman 4-Methylumbelliferyl Palmitate; Purity- Greater Than Or Eq

JWH 018 N-(5-hydroxypentyl) metabolite-d₅ contains five deuterium atoms at the 2, 4, 5, 6, and 7 positions. It is intended for use as an internal standard for the quantification of JWH 018 N-(5-hydroxypentyl) metabolite by GC- or LC-mass spectrometry (MS). JWH 018 is a mildly selective agonist of the peripheral cannabinoid (CB₂) receptor, derived from the aminoalkylindole WIN 55,212-2. The K_i values for binding central cannabinoid (CB₁) and CB₂ receptors are 9.0 and 2.94 nM, respectively, for a CB₁:CB₂ ratio of 3.06. JWH 018 is one of several synthetic CBs which have been included in smoking mixtures. JWH 018 N-(5-hydroxypentyl) metabolite is a major urinary metabolite of JWH 018, characterized by monohydroxylation of the N-alkyl chain. In urine samples, this metabolite is almost completely glucuronidated.

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