We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Share this :
Print
Cayman Pnu 74654; Purity- Greater Than Or Equal To 98%; Size- 1 M
Cayman Pnu 74654; Purity- Greater Than Or Equal To 98%; Size- 1 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$36.00
Your Price
$36.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-16349-1 |
| MFG.PART: | 16349-1 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
The Wnt signaling pathway is integral to normal biological processes and inappropriately active in many cancers. PNU 74654 binds to β-catenin (Kd = 450 nM), inhibiting its interaction with the transcription factor T cell factor 4 (Tcf4) resulting in disruption of the Wnt signaling pathway. Treatment of human adrenocortical cell lines with PNU 74654 significantly reduced expression of several Tcf/β-catenin target genes.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2-
CAS Number
113906-27-7
Molecular Formula
C19H16N2O3
Formula Weight
320.3
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/ml
- DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml
- DMSO: 25 mg/ml
- Ethanol: 1 mg/ml
λmax
318 nm
SMILES
O=C(N/N=C/C1=CC=C(C)O1)C2=CC=CC=C2OC3=CC=CC=C3
InChi Code
InChI=1S/C19H16N2O3/c1-14-11-12-16(23-14)13-20-21-19(22)17-9-5-6-10-18(17)24-15-7-3-2-4-8-15/h2-13H,1H3,(H,21,22)/b20-13+
InChi Key
JJEDWBQZCRESJL-DEDYPNTBSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-16349-1 |
|---|---|
| Supplier Part Number | 16349-1 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/16349m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | US |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 113906-27-7 |