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Cayman 11 Betaprostaglandin F2 Alpha; Purity- Greater Than Or
Cayman 11 Beta -Prostaglandin F2 Alpha ; Purity- Greater Than Or Equal To 98%; Size- 1 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$140.00
Your Price
$140.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-16520-1 |
| MFG.PART: | 16520-1 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
Survivin is a cellular protein implicated in cell survival by interacting with and inhibiting the apoptotic function of several proteins including Smac/DIABLO, caspase-3, and caspase-7., Survivin also plays a role in the regulation of the cell cycle as part of a protein complex that includes INCENP, Aurora B kinase, and Borealin. CAY10625 is an antagonist of the interaction between survivin and the apoptosis-promoting protein Smac/DIABLO, exhibiting an IC50 value of 2.2 µM. It inhibits the interaction of survivin with INCENP less effectively with an IC50 value of 20 µM. CAY10625 is cell-permeable and sensitizes cells to the induction of apoptosis by doxorubicin.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
7-
CAS Number
137346-42-0
Molecular Formula
C25H26N4O4
Formula Weight
446.5
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/ml
- DMSO: 30 mg/ml
- Ethanol: 0.5 mg/ml
λmax
210, 233, 292, 396 nm
SMILES
O=C1C2=CC3=C(C=CC([N+]([O-])=O)=C3)N(CCCCCCCC)C2=NC(N1C4=CC=CC=C4)=O
InChi Code
InChI=1S/C25H26N4O4/c1-2-3-4-5-6-10-15-27-22-14-13-20(29(32)33)16-18(22)17-21-23(27)26-25(31)28(24(21)30)19-11-8-7-9-12-19/h7-9,11-14,16-17H,2-6,10,15H2,1H3
InChi Key
BGABGXIVKDUNFQ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-16520-1 |
|---|---|
| Supplier Part Number | 16520-1 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/16520m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | US |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 38432-87-0 |