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Cayman ()-Cloprostenol; Purity- Greater Than Or Equal To 97%; Siz
NETA PART: | CAYM-16765-1 |
MFG.PART: | 16765-1 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Ursodeoxycholic acid (UDCA) is a secondary bile acid formed via epimerization of chenodeoxycholic acid (CDCA; Item No. )., UDCA is also a metabolite of lithocholic acid (LCA; Item No. ) in human liver microsomes. It inhibits taurocholic acid (Item No. ) uptake in HeLa cells expressing recombinant sodium/taurocholate cotransporting polypeptide (NTCP) with an IC50 value of 3.6 μM. UDCA (50 μM) inhibits apoptosis induced by deoxycholic acid (DCA; Item Nos. | ) or ethanol in primary rat hepatocytes. Dietary administration of UDCA blocks DCA-induced increases in the number of TUNEL-positive hepatocytes in rats. Formulations containing UDCA have been used in the treatment of primary biliary cirrhosis.
WARNING This product is not for human or veterinary use.
Technical Information
- UDCA
- Ursodiol
- DMF: 5 mg/ml
- DMSO: 10 mg/ml
- Ethanol: 15 mg/ml
Shipping & Storage Information
SKU | CAYM-16765-1 |
---|---|
Supplier Part Number | 16765-1 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/16765m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | Y |
CAS Number | 54276-21-0 |