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Cayman Pik-Iii; Purity- Greater Than Or Equal To 98%; Size- 25 Mg
Cayman Pik-Iii; Purity- Greater Than Or Equal To 98%; Size- 25 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$699.00
Your Price
$699.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-17002-25 |
| MFG.PART: | 17002-25 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
PIK-III is an inhibitor of the type 3 phosphatidylinositol 3-kinase (PI3K) vacuolar protein sorting 34 (Vps34) that binds a unique hydrophobic pocket (IC50 = 18 nM).1 It is selective for Vps34 over related PI3K isoforms, PI4Kβ, and mTOR. PIK-III acutely inhibits autophagy and de novo lipidation of LC3, leading to stabilization of autophagy substrates.1
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-(cyclopropyl
CAS Number
1383716-40-2
Synonyms
- Vacuolar Protein Sorting 34 Inhibitor 2
- Vps34-IN2
- Vps34 Inhibitor 2
Molecular Formula
C17H17N7
Formula Weight
319.4
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 10 mg/ml
- DMSO: 15 mg/ml
- DMSO:PBS (pH 7.2) (1:2): 0.33 mg/ml
- Ethanol: 0.14 mg/ml
- PBS (pH 7.2): slightly
λmax
284 nm
SMILES
NC(N=C1)=NC(CC2CC2)=C1C3=CC=NC(NC4=CC=NC=C4)=N3
InChi Code
InChI=1S/C17H17N7/c18-16-21-10-13(15(23-16)9-11-1-2-11)14-5-8-20-17(24-14)22-12-3-6-19-7-4-12/h3-8,10-11H,1-2,9H2,(H2,18,21,23)(H,19,20,22,24)
InChi Key
XXSDLQLNIVFIJI-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-17002-25 |
|---|---|
| Supplier Part Number | 17002-25 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/17002m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | CN |
| ProductLine | CAYM |
| Qty | 25 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 1383716-40-2 |