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Cayman Sgc707; Purity- Greater Than Or Equal To 98%; Size- 1 Mg;
Cayman Sgc707; Purity- Greater Than Or Equal To 98%; Size- 1 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$32.00
Your Price
$32.00
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | CAYM-17017-1 |
MFG.PART: | 17017-1 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Protein arginine N-methyltransferase 3 (PRMT3, Item No. ) is a predominantly cytoplasmic enzyme that is constitutively expressed., SGC707 is a potent allosteric inhibitor of PRMT3 (IC50 = 50 nM) with >100-fold selectivity over other methyltransferases and other non-epigenetic targets. Developed by the , SGC707 avidly binds PRMT3 (Kd = 50 nM by isothermal titration calorimetry) and inhibits the methylation of histones in cells with an IC50 value below 1 µM.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-6-isoquinolinyl -N-[2-oxo-2 -(1-pyrrolidinyl)ethyl] -urea
CAS Number
1687736-54-4
Molecular Formula
C16H18N4O2
Formula Weight
298.3
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 2 mg/ml
- DMSO: 2 mg/ml
- Ethanol: 5 mg/ml
λmax
248, 294 nm
SMILES
O=C(NCC(N1CCCC1)=O)NC2=CC3=CC=NC=C3C=C2
InChi Code
InChI=1S/C16H18N4O2/c21-15(20-7-1-2-8-20)11-18-16(22)19-14-4-3-13-10-17-6-5-12(13)9-14/h3-6,9-10H,1-2,7-8,11H2,(H2,18,19,22)
InChi Key
DMIDPTCQPIJYFE-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
SKU | CAYM-17017-1 |
---|---|
Supplier Part Number | 17017-1 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/17017m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 1687736-54-4 |