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Cayman Pf-543; Purity- Greater Than Or Equal To 98%; Size- 10 Mg
NETA PART: | CAYM-17034-10 |
MFG.PART: | 17034-10 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Benazepril is a prodrug of the angiotensin converting enzyme (ACE) inhibitor benazeprilat (Item No. ). It is metabolized to benazeprilat by hepatic esterases. Benazepril inhibits the in vitro enzymatic activity of partially purified ACE isolated from rabbit lung (IC50 = 2 nM). It decreases the triglyceride and total cholesterol levels in normotensive rats when administered at a dose of 30 mg/kg and decreases aortic atherosclerosis in cholesterol-fed rabbits when administered at a dose of 3 mg/kg per day. Benazepril (0.1-10 mg/kg per day) reduces blood pressure in spontaneously hypertensive rats. It also decreases proteinuria in cats with chronic kidney disease when administered at doses ranging from 0.5 to 1 mg/kg per day. Formulations containing benazepril have been used to treat hypertension, congestive heart failure, and chronic kidney disease in both human and veterinary medicine.
WARNING This product is not for human or veterinary use.
Technical Information
- CGS 14824A
- DMF: 30 mg/ml
- DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml
- DMSO: 20 mg/ml
- Ethanol: 1 mg/ml
Shipping & Storage Information
SKU | CAYM-17034-10 |
---|---|
Supplier Part Number | 17034-10 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/17034m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | CN |
ProductLine | CAYM |
Qty | 10 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | Y |
CAS Number | 1706522-79-3 |