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Cayman Sb-269970 (Hydrochloride); Purity- Greater Than Or Equal T
Cayman Sb-269970 (Hydrochloride); Purity- Greater Than Or Equal To 98%; Size- 25 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$410.00
Your Price
$410.00
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | CAYM-17081-25 |
MFG.PART: | 17081-25 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
The transduction of neurobehavioral effects by serotonin (5-hydroxy tryptamine; 5-HT) is mediated by at least seven major 5-HT receptor subtypes. SB-269970 is a potent 5-HT7A antagonist (pKi = 8.9) that demonstrates >50-fold binding selectivity over 5-HT5A and >250-fold selectivity over 5-HT1, 5-HT2, 5-HT4, 5-HT6, adrenergic α1, dopamine D2, and dopamine D3 receptors.1 It is also reported to block adrenergic α2 receptors in guinea pig vas deferens.2 SB-269970 has been used to target the 5-HT7 receptor in the study of schizophrenia-like cognitive deficits.3
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
3-[[(2R)-2-[2-(4-methyl-1-piperidinyl)ethyl]-1-pyrrolidinyl]sulfonyl]-phenol, monohydrochloride
CAS Number
261901-57-9
Molecular Formula
C18H28N2O3S • HCl
Formula Weight
389.0
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 50 mg/ml
- DMSO: 50 mg/ml
- Ethanol: 5 mg/ml
- PBS (pH 7.2): 1 mg/ml
λmax
286 nm
SMILES
OC1=CC=CC(S(N2CCC[C@@H]2CCN3CCC(C)CC3)(=O)=O)=C1.Cl
InChi Code
InChI=1S/C18H28N2O3S.ClH/c1-15-7-11-19(12-8-15)13-9-16-4-3-10-20(16)24(22,23)18-6-2-5-17(21)14-18;/h2,5-6,14-16,21H,3-4,7-13H2,1H3;1H/t16-;/m1./s1
InChi Key
XQCJOYZLWFNDIO-PKLMIRHRSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
SKU | CAYM-17081-25 |
---|---|
Supplier Part Number | 17081-25 |
UM | EA |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/17081m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 261901-57-9 |