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Cayman 2-Mapb (Hydrochloride); Purity- Greater Than Or Equal To 9
Cayman 2-Mapb (Hydrochloride); Purity- Greater Than Or Equal To 98%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$356.00
Your Price
$356.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-17140-5 |
| MFG.PART: | 17140-5 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
T2AA is an inhibitor of proliferating cell nuclear antigen (PCNA). It inhibits protein-protein interactions between PCNA and a PIP-box-containing peptide (IC50 = 1 μM) and full-length p21 as well as reduces cellular colocalization of PCNA and DNA polymerase δ. T2AA inhibits DNA replication and cell growth in U2OS and HeLa cells in a concentration-dependent manner and induces cell cycle arrest at the S phase when used at a concentration of 20 μM. It also increases DNA double strand break formation induced by cisplatin (Item No. ) in a neutral comet assay and cisplatin-induced inhibition of clonogenic survival in HeLa and U2OS cells.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
βS-amino-4-
CAS Number
2138331-07-2
Synonyms
- T2-amino Alcohol
Molecular Formula
C15H15I2NO3 • HCl
Formula Weight
547.6
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/ml
- DMSO: 30 mg/ml
- Ethanol: 30 mg/ml
- Ethanol:PBS (pH 7.2) (1:8): 0.11
λmax
229 nm
SMILES
OC(C=C1)=CC=C1OC2=C(I)C=C(C[C@H](N)CO)C=C2I.Cl
InChi Code
InChI=1S/C15H15I2NO3.ClH/c16-13-6-9(5-10(18)8-19)7-14(17)15(13)21-12-3-1-11(20)2-4-12;/h1-4,6-7,10,19-20H,5,8,18H2;1H/t10-;/m0./s1
InChi Key
ILDRWUYIAXQKLH-PPHPATTJSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-17140-5 |
|---|---|
| Supplier Part Number | 17140-5 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/17140m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | US |
| ProductLine | CAYM |
| Qty | 5 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 100389-74-0 |