We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Share this :
Print
Cayman O-3m3fbs; Purity- Greater Than Or Equal To 98%; Size- 5 Mg
Cayman O-3m3fbs; Purity- Greater Than Or Equal To 98%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$86.00
Your Price
$86.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-17251-5 |
| MFG.PART: | 17251-5 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
Kynurenic acid is an active metabolite of tryptophan (Item No. | ). It is formed from tryptophan via a kynurenine (Item No. ) intermediate by kynurenine aminotransferases (KATs). Kynurenic acid is an antagonist of the NMDA and AMPA receptors as well as α7 nicotinic acetylcholine receptors (nAChRs; EC50s = 235, 101, and 7 µM, respectively). It is also an agonist of the aryl hydrocarbon receptor (AhR) and G protein-coupled receptor 35 (GPR35; EC50s = 1.4 and 39 µM, respectively). It prevents lesioned hemisphere weight loss in a neonatal rat model of cerebral hypoxic-ischemia induced by carotid artery ligation when administered at a dose of 300 mg/kg. Kynurenic acid (1 and 5 mg/ml) is protective against rhabdomere neurodegeneration in the eye in an Htt93Q transgenic Drosophila model of Huntingtons disease. Levels of kynurenic acid in cerebrospinal fluid are increased in patients with schizophrenia.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-hydroxy-2-
CAS Number
345909-35-5
Synonyms
- KYNA
Molecular Formula
C10H7NO3 • XH2O
Formula Weight
189.2
Purity
≥98%
Formulation
A crystalline solid
Solubility
- 0.1 M NaOH: 1 mg/ml
λmax
217, 247, 341 nm
SMILES
OC(C1=NC2=CC=CC=C2C(O)=C1)=O
InChi Code
InChI=1S/C10H7NO3/c12-9-5-8(10(13)14)11-7-4-2-1-3-6(7)9/h1-5H,(H,11,12)(H,13,14)
InChi Key
HCZHHEIFKROPDY-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-17251-5 |
|---|---|
| Supplier Part Number | 17251-5 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/17251m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | US |
| ProductLine | CAYM |
| Qty | 5 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 313981-55-4 |