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Cayman Ng 52; Purity- Greater Than Or Equal To 98%; Size- 1 Mg
Cayman Ng 52; Purity- Greater Than Or Equal To 98%; Size- 1 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$62.00
Your Price
$62.00
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | CAYM-17309-1 |
MFG.PART: | 17309-1 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Cefotiam is a broad-spectrum cephalosporin antibiotic. It inhibits the growth of the Gram-positive bacterium S. aureus (MIC50 = 0.26 µg/ml) and the Gram-negative bacteria P. aeruginosa, E. coli, and H. influenzae (MIC50s = 1, 0.06, and 0.01 µg/ml, respectively). Cefotiam increases survival in mouse models of infection with the 853E and 630E strains of S. aureus (ED50s = 3.5 and 8.3 mg/kg, respectively) and various strains of E. coli (ED50s = 0.5-25 mg/kg). Formulations containing cefotiam have previously been used in the treatment of bacterial infections.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(6R,7R)-7-[[2-(2-amino-4-thiazolyl)acetyl]amino]-3-[[[1-[2-(dimethylamino)ethyl]-1H-tetrazol-5-yl]thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, dihydrochloride, hydrate
Synonyms
- Cephotiam
- CGP 14221
- CGP 14221/E
- CTM
- SCE 963
Molecular Formula
C18H23N9O4S3 • 2HCl [XH2O]
Formula Weight
598.5
Purity
≥80%
Formulation
A crystalline solid
Solubility
- DMF: 5 mg/ml
- DMSO: 10 mg/ml
- PBS (pH 7.2): 10 mg/ml
λmax
259 nm
SMILES
OC(C1=C(CS[C@@]2([C@H](NC(CC3=CSC(N)=N3)=O)C(N21)=O)[H])CSC4=NN=NN4CCN(C)C)=O.Cl.Cl.O
InChi Code
InChI=1S/C18H23N9O4S3.2ClH.H2O/c1-25(2)3-4-26-18(22-23-24-26)34-7-9-6-32-15-12(14(29)27(15)13(9)16(30)31)21-11(28)5-10-8-33-17(19)20-10;;;/h8,12,15H,3-7H2,1-2H3,(H2,19,20)(H,21,28)(H,30,31);2*1H;1H2/t12-,15-;;;/m1.../s1
InChi Key
KHUCCKUOJMXYKH-BUWDDJPCSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 4 years
SKU | CAYM-17309-1 |
---|---|
Supplier Part Number | 17309-1 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/17309m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 212779-48-1 |