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Cayman Pf-3716556; Purity- Greater Than Or Equal To 98%; Size- 10
Cayman Pf-3716556; Purity- Greater Than Or Equal To 98%; Size- 10 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$109.00
Your Price
$109.00
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | CAYM-17710-10 |
MFG.PART: | 17710-10 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
PF-3716556 is a potent and selective hydrogen-potassium pump (H+/K+-ATPase) inhibitor in a new class of acid suppressants, the potassium-competitive acid blockers or acid pump antagonists. PF-3716556 inhibited H+/K+-ATPase activity in porcine membrane vesicles, as well as canine and human recombinant cells under ion-leaky conditions (pIC50s = 6.026, 6.038, and 6.009, respectively). PF-3716556 showed 3-fold greater inhibition than revaprazan in ion-tight (neutral pH) conditions.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
8-[[(4R)-3,4- dihydro-5- methyl-2H-1- benzopyran-4- yl]amino]-N- (2-hydroxy ethyl)-N,2- dimethyl- imidazo[1,2 -a]pyridine-6 -carboxamide
CAS Number
928774-43-0
Molecular Formula
C22H26N4O3
Formula Weight
394.5
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/ml
- DMSO: 30 mg/ml
- DMSO:PBS (pH 7.2) (1:20): 0.04 mg/ml
- Ethanol: 10 mg/ml
λmax
254, 297 nm
SMILES
CC1=CN2C=C(C=C(C2=N1)N[C@@H]3CCOC4=C3C(C)=CC=C4)C(N(CCO)C)=O
InChi Code
InChI=1S/C22H26N4O3/c1-14-5-4-6-19-20(14)17(7-10-29-19)24-18-11-16(22(28)25(3)8-9-27)13-26-12-15(2)23-21(18)26/h4-6,11-13,17,24,27H,7-10H2,1-3H3/t17-/m1/s1
InChi Key
YBHKBMJREUZHOV-QGZVFWFLSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
SKU | CAYM-17710-10 |
---|---|
Supplier Part Number | 17710-10 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/17710m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | CN |
ProductLine | CAYM |
Qty | 10 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 928774-43-0 |