We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Share this :
Print
Cayman Czc-54252; Purity- Greater Than Or Equal To 98%; Size- 5 M
Cayman Czc-54252; Purity- Greater Than Or Equal To 98%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$130.00
Your Price
$130.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-17998-5 |
| MFG.PART: | 17998-5 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
CZC-54252 is an inhibitor of leucine-rich repeat kinase 2 (LRRK2; IC50s = 1.28 and 1.85 nM for wild-type and G2019S mutant forms of LRRK2, respectively).1 It has been shown to protect against neuronal injury induced by Parkinson’s disease-related LRRK2-G2019S mutant activity in primary human neurons with an EC50 value of 1 nM.2
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-[2-[[5-
CAS Number
1191911-27-9
Molecular Formula
C22H25ClN6O4S
Formula Weight
505.0
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 20 mg/mL
- DMF:PBS(pH 7.2)(1:1): 0.5 mg/mL
- DMSO: 10 mg/mL
λmax
282 nm
SMILES
COC1=CC(N2CCOCC2)=CC=C1NC3=NC=C(Cl)C(NC4=CC=CC=C4NS(C)(=O)=O)=N3
InChi Code
InChI=1S/C22H25ClN6O4S/c1-32-20-13-15(29-9-11-33-12-10-29)7-8-19(20)26-22-24-14-16(23)21(27-22)25-17-5-3-4-6-18(17)28-34(2,30)31/h3-8,13-14,28H,9-12H2,1-2H3,(H2,24,25,26,27)
InChi Key
CLGWUCNXOBLWFM-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-17998-5 |
|---|---|
| Supplier Part Number | 17998-5 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/17998m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | CN |
| ProductLine | CAYM |
| Qty | 5 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 1191911-27-9 |