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Cayman Nvp-Adw742; Purity- Greater Than Or Equal To 98%; Size- 10
Cayman Nvp-Adw742; Purity- Greater Than Or Equal To 98%; Size- 10 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$188.00
Your Price
$188.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-18390-10 |
| MFG.PART: | 18390-10 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
NVP-ADW742 is an insulin-like growth factor 1 receptor (IGF-1R) inhibitor with an IC50 value of 0.17 µM.1 It exhibits 6-fold greater selectivity for IGF-1R over the insulin receptor (InsR) kinase and minimal inhibitory activity against c-Kit, HER1, PDGFR, VEGFR2, or Bcr-Abl p210.1 NVP-ADW742 has been shown to inhibit tumor proliferation both in vitro and in a mouse model of multiple myeloma.1
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
5-[3-
CAS Number
475488-23-4
Synonyms
- ADW742
- GSK552602A
Molecular Formula
C28H31N5O
Formula Weight
453.6
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 30 mg/mL
- DMSO: 30 mg/mL
- Ethanol: 30 mg/mL
- Ethanol:PBS (pH 7.2) (1:10): 0.09 mg/mL
λmax
288 nm
SMILES
NC1=NC=NC2=C1C(C3=CC=CC(OCC4=CC=CC=C4)=C3)=CN2[C@@H]5C[C@@H](CN6CCCC6)C5
InChi Code
InChI=1S/C28H31N5O/c29-27-26-25(22-9-6-10-24(15-22)34-18-20-7-2-1-3-8-20)17-33(28(26)31-19-30-27)23-13-21(14-23)16-32-11-4-5-12-32/h1-3,6-10,15,17,19,21,23H,4-5,11-14,16,18H2,(H2,29,30,31)/t21-,23-
InChi Key
LSFLAQVDISHMNB-AFARHQOCSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-18390-10 |
|---|---|
| Supplier Part Number | 18390-10 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/18390m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | US |
| ProductLine | CAYM |
| Qty | 10 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 475488-23-4 |