We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Cayman Cx-5461; Purity- Greater Than Or Equal To 98%; Size- 10 Mg
NETA PART: | CAYM-18392-10 |
MFG.PART: | 18392-10 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Sulfamethoxazole is a sulfonamide antibiotic. It inhibits growth of E. coli (MIC = 10 μg/ml) and clinical isolates of methicillin-resistant S. aureus (MRSA; MICs = 25-50 μg/ml)., Sulfamethoxazole, in combination with trimethoprim (Item No. ) at a ratio of 20:1, inhibits growth of MRSA in vivo in mice (MIC = 0.8 μg/ml; ED50s = 6.4 and 9.6 mg/kg for two MRSA strains). In a mouse model of urinary tract infection with E. coli, a combination of sulfamethoxazole and trimethoprim decreases recurrent infection when administered for 10 days. Sulfamethoxazole acts by inhibiting dihydropteroate synthase (DHPS), which converts a pteridine and 4-aminobenzoic acid (PABA; Item No. ) to dihydropteroate, an intermediate in folate biosynthesis. It inhibits recombinant P. carinii DHPS (IC50 = 23 nM; Ki = 7.5 nM) and folate biosynthesis in situ by 48.6%. Formulations containing sulfamethoxazole and trimethoprim have been used to treat bronchitis, prostatitis, and urinary tract infections among other infectious conditions.
WARNING This product is not for human or veterinary use.
Technical Information
- NSC 147832
- Ro 4-2130
- DMF: 50 mg/ml
- DMSO: 50 mg/ml
- DMSO:PBS (pH 7.2) (1:2): 0.5 mg/ml
- Ethanol: 0.25 mg/ml
Shipping & Storage Information
SKU | CAYM-18392-10 |
---|---|
Supplier Part Number | 18392-10 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/18392m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 10 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 1138549-36-6 |