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Cayman Fexinidazole; Purity- Greater Than Or Equal To 98%; Size-
Cayman Fexinidazole; Purity- Greater Than Or Equal To 98%; Size- 1 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$44.00
Your Price
$44.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-18393-1 |
| MFG.PART: | 18393-1 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
Fexinidazole is an antiparasitic agent. It is active against 15 strains of T. brucei, including T. b. rhodesiense, T. b. brucei, and T. b. gambiense (IC50s = 0.95-3.31 µM). Fexinidazole inhibits the growth of L. donovani at the promastigote and axenic amastigote stages (EC50s = 5.6 and 2.8 µM, respectively). Fexinidazole (50 to 30 mg/kg per day) reduces parasitic burden and increases survival in a mouse model of infection with benznidazole-susceptible, -partially resistant, or -resistant T. cruzi. Formulations containing fexinidazole have been used in the treatment of African sleeping sickness and Chagas disease.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
1-methyl-2-
CAS Number
59729-37-2
Synonyms
- HOE239
Molecular Formula
C12H13N3O3S
Formula Weight
279.3
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 20 mg/ml
- DMF:PBS (pH 7.2) (1:8): 0.11 mg/ml
- DMSO: 10 mg/ml
- Ethanol: 0.2 mg/ml
λmax
227, 257, 299 nm
SMILES
CSC1=CC=C(OCC2=NC=C([N+]([O-])=O)N2C)C=C1
InChi Code
InChI=1S/C12H13N3O3S/c1-14-11(13-7-12(14)15(16)17)8-18-9-3-5-10(19-2)6-4-9/h3-7H,8H2,1-2H3
InChi Key
MIWWSGDADVMLTG-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-18393-1 |
|---|---|
| Supplier Part Number | 18393-1 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/18393m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | US |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 59729-37-2 |