Cayman Cyt997; Purity- Greater Than Or Equal To 98%; Size- 50 Mg

CYT997 is an inhibitor of microtubule polymerization (IC₅₀ = ~3 µM).¹ It induces cell cycle arrest at the G₂/M phase and is cytotoxic against a panel of cancer cell lines (IC₅₀s = 0.009-0.101 µM). CYT997 increases human umbilical vein endothelial cell (HUVEC) monolayer permeability (IC₅₀ = ~0.08 µM), a marker of vascular collapse. It decreases liver metastasis in a murine DMH-induced colon cancer model when administered at doses of 5, 10, and 15 mg/kg.²

WARNING This product is not for human or veterinary use.