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Cayman A-77-01; Purity- Greater Than Or Equal To 98%; Size- 1 Mg
NETA PART: | CAYM-18396-1 |
MFG.PART: | 18396-1 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Rebamipide is a gastroprotective agent and mucin secretagogue. It increases the levels of prostaglandin E2 (PGE2) and COX-2 in rat gastric mucosa when administered at doses of 15 and 50 mg/kg per day. Rebamipide (30 and 100 mg/kg, i.p.) prevents the formation of gastric ulcers induced by absolute ethanol, sodium hydroxide, or hydrochloric acid in rats, an effect that can be blocked by the non-selective COX inhibitor indomethacin (Item No. ). It also increases the production of mucin 16 in stratified corneal epithelial cells in vitro when used at concentrations of 10 and 100 µM. Rebamipide (1% w/v) increases the levels of mucin-like substances in rabbit conjunctiva and cornea and, in a rabbit model of dry eye disease, reduces desiccation-induced corneal damage. Formulations containing rebamipide have been used in the treatment of peptic ulcer disease and dry eye disease.
WARNING This product is not for human or veterinary use.
Technical Information
- OPC 12759
- DMF: 1 mg/ml
- DMSO: 1 mg/ml
- DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml
Shipping & Storage Information
SKU | CAYM-18396-1 |
---|---|
Supplier Part Number | 18396-1 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/18396m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 607737-87-1 |