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Cayman Ri-2; Purity- Greater Than Or Equal To 98%; Size- 5 Mg
Cayman Ri-2; Purity- Greater Than Or Equal To 98%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$249.00
Your Price
$249.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-18397-5 |
| MFG.PART: | 18397-5 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
ITH15004 is a non-nucleotide antagonist of the purinergic P2X7 receptor (IC50 = 9 µM in HEK293 cells expressing the human receptor). It inhibits ATP-induced currents in X. laevis oocytes expressing the human P2X7 receptor when used at a concentration of 100 µM. ITH15004 (1 µM) decreases IL-1β release from LPS-primed, ATP-stimulated isolated mouse peritoneal macrophages. It has high permeability in a parallel artificial membrane permeability assay (PAMPA).
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2-(6-chloro-
CAS Number
2600675-12-3
Molecular Formula
C13H7Cl3N4O
Formula Weight
341.6
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 20 mg/ml
- DMF:PBS (pH 7.2) (1:3): 0.25 mg/ml
- DMSO: 10 mg/ml
λmax
260 nm
SMILES
O=C(C1=CC=C(Cl)C=C1Cl)CN2C=NC3=C(Cl)N=CN=C23
InChi Code
InChI=1S/C13H7Cl3N4O/c14-7-1-2-8(9(15)3-7)10(21)4-20-6-19-11-12(16)17-5-18-13(11)20/h1-3,5-6H,4H2
InChi Key
NLRGSGVPLHCTPK-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 2 years
| SKU | CAYM-18397-5 |
|---|---|
| Supplier Part Number | 18397-5 |
| UM | UNIT |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/18397m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | US |
| ProductLine | CAYM |
| Qty | 5 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 1417162-36-7 |