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Cayman Eliprodil; Purity- Greater Than Or Equal To 98%; Size- 5 M
NETA PART: | CAYM-18398-5 |
MFG.PART: | 18398-5 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
2H-Cho-Arg is a steroid-based cationic lipid that contains a 2H-cholesterol skeleton coupled to an L-arginine head group and can be used to facilitate gene transfection. It forms a complex with plasmid DNA (pDNA) and decreases pDNA migration in an electrophoretic mobility shift assay at +/- charge ratios of 4 or higher. 2H-Cho-Arg facilitates transfection of a luciferase gene into H1299 cells, an effect that is reversed by the lipid raft-mediated endocytosis inhibitor methyl-β-cyclodextrin (Item No. ) and the caveolae-mediated endocytosis inhibitor genistein (Item No. ), but not by inhibitors of clathrin- or micropinocytosis-mediated endocytosis. It induces cytotoxicity in H1299 cells (IC50 = 92.7 μg/ml).
WARNING This product is not for human or veterinary use.
Technical Information
- DMF: 50 mg/ml
- DMSO: 50 mg/ml
- Ethanol: 50 mg/ml
- Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/ml
Shipping & Storage Information
SKU | CAYM-18398-5 |
---|---|
Supplier Part Number | 18398-5 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/18398m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 5 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 119431-25-3 |