Cayman 4-Aminopyridine; Purity- Greater Than Or Equal To 95%; Siz

4-Aminopyridine (4-AP) is a non-selective blocker of voltage-dependent K⁺-channels (K_v proteins in the KCN gene family). It has greatest potency at K_v1 (KCNA) and K_v3 (KCNC) family members (IC₅₀s = 290, 590, 195, 13, 29, and 100 µM for subunits 1.1, 1.2, 1.3, 1.4, 3.1, and 3.2, respectively).¹ 4-AP also blocks K_v2 and K_v4 subunits at millimolar concentrations.¹ When administered orally, 4-AP has benefits against multiple sclerosis, while injection into the brain produces epileptiform activity and can be used to study seizures.^2,3,4

WARNING This product is not for human or veterinary use.