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Cayman Sb 239063; Purity- Greater Than Or Equal To 98%; Size- 1 M
Cayman Sb 239063; Purity- Greater Than Or Equal To 98%; Size- 1 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$68.00
Your Price
$68.00
HOW MUCH YOU SAVE:
0.00 %
NETA PART: | CAYM-19142-1 |
MFG.PART: | 19142-1 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
MAP kinase-activated protein kinase 2 (MAPKAP2, MK2) is a stress-activated serine/threonine protein kinase that is phosphorylated by p38 MAP kinase and is involved in diverse cellular functions with a central role in inflammation.,, MK2 inhibitor III is a potent, cell-permeable inhibitor of MK2 (IC50 = 8.5 nM). It less potently blocks MK3 and MK5 (IC50s = 210 and 81 nM, respectively) and is weak or inactive against several other kinases, including other p38 MAP kinase targets. MK2 inhibitor III prevents LPS-
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
1,5,6,7- tetrahydro- 2-[2-(3- quinolinyl)-4- pyridinyl]- 4H-pyrrolo [3,2-c] pyridin-4-one, monohydrate
CAS Number
1186648-22-5
Molecular Formula
C21H16N4O • H2O
Formula Weight
358.4
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMF: 1.4 mg/ml
- DMSO: 5 mg/ml
- DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml
λmax
208, 243, 309 nm
SMILES
O=C(NCC1)C2=C1NC(C3=CC(C4=CC(C=CC=C5)=C5N=C4)=NC=C3)=C2.O
InChi Code
InChI=1S/C21H16N4O.H2O/c26-21-16-11-20(25-18(16)6-8-23-21)14-5-7-22-19(10-14)15-9-13-3-1-2-4-17(13)24-12-15;/h1-5,7,9-12,25H,6,8H2,(H,23,26);1H2
InChi Key
NIKCVKMHGQQSRN-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
SKU | CAYM-19142-1 |
---|---|
Supplier Part Number | 19142-1 |
UM | EA |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/19142m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | CN |
ProductLine | CAYM |
Qty | 1 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 193551-21-2 |