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Cayman Sb 239063; Purity- Greater Than Or Equal To 98%; Size- 500
Cayman Sb 239063; Purity- Greater Than Or Equal To 98%; Size- 500 Micrograms; - CAYM (Additional S&H Or Hazmat Fees May Apply)
List Price
$37.00
Your Price
$37.00
HOW MUCH YOU SAVE:
0.00 %
| NETA PART: | CAYM-19142-500 |
| MFG.PART: | 19142-500 |
| UNSPSC: | 12352200 |
| Manufacturer: | Cayman |
Product Description
SB 239063 is a selective p38 MAPK inhibitor (IC50 = 44 nM for recombinant purified p38α).1 It displays greater than 220-fold selectivity for p38 MAPK over ERK, JNK1, and other kinases.1 SB 239063 has been shown to reduce inflammatory cytokine production in lipopolysaccharide-stimulated human peripheral blood monocytes (IC50s = 0.12 and 0.35 µM, respectively for IL-1 and TNF-α) and is neuroprotective following oral administration in a rat model of cerebral focal ischemia.1,2
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
trans-
CAS Number
193551-21-2
Molecular Formula
C20H21FN4O2
Formula Weight
368.4
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 10 mg/ml
- DMSO: 16 mg/ml
- DMSO:PBS (pH 7.2) (1:6): 0.14 mg/ml
- Ethanol: 0.25 mg/ml
λmax
232, 268, 317 nm
SMILES
O[C@@H](CC1)CC[C@H]1N2C(C3=CC=NC(OC)=N3)=C(C4=CC=C(F)C=C4)N=C2
InChi Code
InChI=1S/C20H21FN4O2/c1-27-20-22-11-10-17(24-20)19-18(13-2-4-14(21)5-3-13)23-12-25(19)15-6-8-16(26)9-7-15/h2-5,10-12,15-16,26H,6-9H2,1H3/t15-,16-
InChi Key
ZQUSFAUAYSEREK-WKILWMFISA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-19142-500 |
|---|---|
| Supplier Part Number | 19142-500 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | https://www.caymanchem.com/msdss/19142m.pdf |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | CN |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.00 |
| Lead Time | 2 Business Days |
| Hazardous | N |
| CAS Number | 193551-21-2 |