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Cayman Xen445; Purity- Greater Than Or Equal To 98%; Size- 10 Mg
NETA PART: | CAYM-19144-10 |
MFG.PART: | 19144-10 |
UNSPSC: | 12352200 |
Manufacturer: | Cayman |
Product Description
Daunorubicin-13C-d3 is intended for use as an internal standard for the quantification of daunorubicin (Item No. ) by GC- or LC-MS. Daunorubicin is an antitumor antibiotic. At 0.2-1 μM, daunorubicin induces apoptosis in mature monocytic U937 and myelocytic HL-60 acute myeloid leukemia (AML) cells. However, immature AML cells (CD34+-KG1a, -KG1, or -HEL cells) appear resistant to apoptosis at similar concentrations. In mature AML cells, daunorubicin has been shown to trigger a reactive oxygen species-dependent sphingomyelin-ceramide pathway that activates the MEKK1-SEK1-JNK cascade leading to enhanced DNA binding activity of the transcription factor AP-1.,
WARNING This product is not for human or veterinary use.
Technical Information
- DMSO: slightly soluble
Shipping & Storage Information
SKU | CAYM-19144-10 |
---|---|
Supplier Part Number | 19144-10 |
UM | UNIT |
UNSPSC | 12352200 |
Manufacturer | Cayman |
MSDS URL | https://www.caymanchem.com/msdss/19144m.pdf |
Temperature | -20 |
Refrigerated-Frozen | Refrigerated |
CountryOfOrigin | US |
ProductLine | CAYM |
Qty | 10 |
MinOrderQty | 1 |
Weight | 7.00 |
Lead Time | 2 Business Days |
Hazardous | N |
CAS Number | 1515856-92-4 |